If you feel frustrated with experiments that did not turn out as expected, you are not alone.
History is full of innovators going through repetitive failures before major breakthroughs.
The notion of failure is relative; each experiment likely contains some sort of success or lessons that can be learned.
Documenting these (in your paper draft or experiment log) can add a sense of what you have achieved so far, and how to plan future tasks.
If you are really exhausted, switch to do something else (e.g., another project) or just take a break, and see if that could bring a fresh perspective into your work.
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